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Indications and biopsii depending on data spermogrammy also are discussed till now. One researchers (Mosca and soavt., 1982) consider, that biopsija it is shown in all cases of barreness at men at concentration spermatozoonov below 25-20 million/ml, others (Е1-Bayaumi and soavt., 1982) recommend to do biopsiju to all men, suffering barreness, at concentration spermatozoonov less than 5 million/ml
According to the experience of our clinic based on carrying out 580 biopsy, considered operation is the higher and last diagnostic step which follows or new rational treatment, or the termination of any treatment.
There are absolute and relative indications to carrying out biopsii. Absolute indications - azoospermija in the presence of accessible for biopsii jaichek; relative indications - oligozoospermija III-IV degrees It is long not giving in to correction.
If all used methods do not give full representation about a condition of impregnating function, in particular at maloobjasnimyh azoospermijah and not giving in to treatment oligozoospermijah, is shown intsizionnaja biopsija jaichka. Abroad widely practise biopsii with the help punktsionnoj needles (Iikolov, Papazov, 1971), Negative sides of last method - impossibility to examine parenhimu jaichka, to choose malososudistyj a site for biopsii in this connection at punktsionnoj biopsii the big trauma can be put, than at intsizionnoj.
The Taken fabric jaichka immerse in a clamp (10% a solution of neutral formalin) and after special conductings make patogistologicheskoe research at which changes in seed kanaltsah and mezhutochnoj fabrics are established. In kanaltsah the condition mitoticheskoj and mejoticheskoj phases spermatogeneza is marked. These data have essentially great value for a choice of medical products. In particular, at infringements in mitoticheskoj spermatogeneza application gopadotropyh type preparations follitropiia is shown a phase, and infringement in mejoticheskoj is stopped to a phase by application apdrogennyh preparations. On a condition interstitsialnyh endokrinotsitov function jaichka is defined androgennaja.
The Estimation of changes of a hormonal condition. In case clinical data do not give clear representation about character and degree endokrinnyh infringements, simple laboratory tests and difficult laboratory methods of research are used.
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