you are: ILLNESS the CRONE

Key sign of illness the Crone at a pas-tologo-anatomic research - a nonspecific inflammation of all thickness of a wall of the amazed body. Usually transmuralnyj character of defeat is traced already at early stages of disease. The macroscopical picture of illness the Crone is characterised utolshchennoj, otechnoj bryzhejkoj: finger-shaped vypjachivanija utolshchennoj bryzhejki it is characteristic extend on all serous cover. Bryzheechnye lymph nodes can be accustomed to drinking together, forming conglomerates. In amazed bryzhejke and on a serous cover sometimes happen the expanded lymphatic vessels are visible. The mucous membrane condition is defined by weight of disease and prevalence of process. At opening of the amazed segment of a gut in one cases find out only insignificant giperemiju and the mucous membrane hypostasis, in others - architecture of a mucous membrane is broken at the expense of the knotty (hilly) hypostasis alternating with deep ulcers. Ulcers, as a rule, linear traces reminding under the form grabel, tend to extend in a longitudinal direction. They can be observed and against not changed mucous membrane. Ulcers are various on depth, but get in podslizistyj and muscular layers where, incorporating among themselves, form big intramu-ralnyj the channel more often. In this connection a serous cover and bryzhejka regularly inflame. From here one of characteristic lines of illness the Crone - the tendency of the amazed loops to be accustomed to drinking among themselves peritonealnymi fibrous tjazhami. Adgezivnyj process often becomes complicated fistulas which can be considered as the second prominent feature of illness the Crone.

It is supposed, that fistulas originate from ulcers which gradually get into a serous cover and the next loops of guts. Such fistulas are formed between loops of a thick and thin gut or between loops of the thin. They can penetrirovat a skin and to leave outside. As the Most frequent locations of external apertures svishchevyh courses are considered a navel and promezhnost. If at illness the Crone is amazed a rectum, the ulcers formed in rektalnyh kriptah, can get in pararektalnuju kletchatku, forming an abscess, or in analnyj the channel where are amazed sfinktery and muscles supporting them.

Faltering (segmentary) character of an inflammation is observed at 75-85% sick of illness the Crone. In the piece of the gut located between two amazed segments, as a rule, does not come to light neither macroscopical, nor microscopic changes. However it is noticed, that not changed site of the gut located proksimalnee amazed segment, often happens is expanded.

mikroskopicheski illness the Crone is shown inflammatory infiltratsiej, an intestinal wall extending in deep layers. Despite transmuralnyj character of defeat, the greatest changes reveal in podslizistom a layer, which as a result of a hypostasis considerably utolshchaetsja. At process progressing in it find gialinizatsiju vessels and fibroz. The fullest information on illness the Crone at histologic research give shchelevidnye ulcers and granulemy with multinuclear huge cages.

Results of numerous researches show, that granulemy at illness the Crone it is possible to find out in all layers of an intestinal wall, and also in lymph nodes and bryzhejke. The revealing percent granulem fluctuates from 40 to 85. In bioptatah they are defined much less often, than in macropreparations.