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  •   DIAGNOSTICS. Immunologichesky tests

    you are: DIAGNOSTICS

    Immunologichesky tests. The big theoretical and practical value have immunologicheskie aspects of man's barreness. Original researches of Dutch scientists Rumke, Hellinga (1954, 1959) have drawn the big attention to studying autoimmunizatsii own sperm. They have shown, that spermatoaggljutininami can be teplostojkie scale-globuliny and lipoproteidy. Further these data have been confirmed and added Bandhauer with co-authors (1964) who have found out in plasma of sperm of 8-9 antigene fractions responsible for autoimmunizatsiju by elements ejakuljata. Etiologichesky factors autoimmunnyh processes can be variety of influences. In particular, changes rn environments in the sour party, feverish conditions with a body heat, an ischemia and gipoksija jaichka, an avitaminosis, present in ejakuljate medicinal, infectious agents, chronic inflammatory processes in additional glands.

    Spent by us kliniko-immunologicheskie researches sick of a chronic prostatitis with functional infringements (I.F.Junda and soavt., 1975, 1976, 1989) have shown, that at infringement of fruitfulness at patients with a chronic prostatitis are defined autoantitela to fabrics predstatelnoj glands, jaichka and to spermatozoonam. In parallel with it changes of the general reaktivkosti are noted, approximately in 20% of supervision it has been lowered, in 35% - normal and in 45% - is raised. These changes, apparently, are consequences infitsirovanija.

    From the told follows, that immunologichesky a background at barreness at men difficult enough and variabelnyj. Definitions immunologicheskih changes at barreness at men should be carried out with use of a complex of special methods of research. In our establishment are with that end in view applied: reaction spermatoaggljutinatsii Franklin - Djuksa (1964), reaction spermatoimmobilizatsii on izodzhima (1968), reaction passive gemaggljutinatsii on A.D.Ado, A.A.Polneru (1963), linkage reaction komplementa on 50% gemolizu on O.E.Vjazovu (1967), - reaction SHtefena on method Vershigory (1971), immunoelektroforez on L.A.Zilberu and G.A.Abelevu (1962), cellular hypersensitivity is defined on limfotsitotoksichnosti, ingibitsii and migrations of leukocytes in an agar, caused by an antigene predstatelnoj glands of the person on Klauset П97П.

    The Immunologichesky changes expressed in different degree, were defined approximately at 50% sick of the chronic prostatitis, suffering by fruitfulness infringement.

    Thus, recognition of barreness at men without taking into account immunologicheskih shifts does not give full representation about geneze patospermii.